Amoxicillin; operation, application, and side effects

Health gorlax August 8, 2016 5 1
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Amoxicillin is a broad spectrum antibiotic. It is used as a remedy against both gram-negative and gram-positive bacteria. Amoxycillin is the most widely used antibiotics in the Netherlands, and is brought on the market under different names. The best known is probably Clamoxyl, but other brands are: Actimoxi, Amoxil, Amoxibiotic, Amoxicilina and Pamoxicillin.

Amoxicillin operation

Amoxicillin is a bactericidal agent selected from the group consisting of penicillins. It is the second most used drug in the Netherlands. It is applied in the treatment of infections caused by gram positive and negative bacteria. Because of this, it is an antibiotic that can be used against a very wide spectrum of different bacteria. The group of penicillin derived antibiotics are also known as penicillin derivatives. In addition to amoxicillin also fall within this group carbapenem, monobactam, cephalosporin and carboxypenicilline. All penicillin works almost the same mechanism. The active substance in amoxicillin, beta-lactam, prevents the synthesis of the bacterial cell wall, through blockade of the bacterial DD-transpeptidase enzyme. This allows the bacteria can no longer multiply.

Dosage and route of administration of amoxicillin

You can Amoxicillin capsules before, during or after meals.
For adults and children over 10 years:
  • Two times a day, 500 to 750 mg, or three times a day, 375-500mg per day
For children between 3 and 10 years:
  • 375mg twice a day or three times a day, 250mg per day

Contraindication amoxicillin

You may not use amoxixilline when you:
  • Suffer from liver dysfunction.
  • Jaundice, when it previously caused by this drug.
  • Allergic or hypersensitive to this drug or other antobiotica from the penicillin or cephalosporins.
  • Are pregnant and Phenylketones has in the urine, this is related to sensitivity to aspartame and phenylalanine.
  • Are younger than 12 and has Phenylketones in the urine, for the same reasons as mentioned above in pregnant women.

Amoxicillin at pregnancy

There are not sufficient data to assess adequately the potential damage caused by this drug during pregnancy. It is therefore strongly advised not to use this drug during pregnancy unless the doctor specifically prescribes.

Amoxicillin and breastfeeding

The active substance of amoxicillin is excreted in breast milk. The result may be that the infant builds allergy to this substance and burden of developing diarrhea. Therefore the manufacturer recommends to be careful with its use during lactation.

Amoxicillin Side Effects

Amoxicillin has several side effects. Most side effects are relatively mild and increase as the dosage and duration of use increases. Most side effects are caused by the fact that amoxicillin not only address the pathogenic bacteria but also kills the bacteria of the intestinal flora. Expected side effects include:
  • Vomit
  • Bellyache
  • Diarrhea
  • Digestive Disorders
  • Anal itching
  • Skin reactions, allergic
  • Gastrointestinal disorders
  • Nausea
  • Stools, brijig
  • Rashes caused by allergy

Driving and using heavy machinery

This drug can cause side effects and the symptoms may make you drive less. Avoid driving or operating hazardous machinery unless you're feeling well.

Interact with other medications

Amoxicillin may interact with other medications. In particular, the concomitant use of other antibiotics can be harmful. Other drugs which have the potential to interact with the use of amoxicillin:
  • Aspirin or lAcetylsalicylzuur
  • Indomethacin
  • Sulfinpyrazone
  • Allopurinol
  • Probenecid
  • Aminoglycoside antibiotics
  • Phenylbutazone
  • Oxyphenbutazone
  • Contraceptive pills: there is a chance that the pill is not fully reliable.
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