Dermatitis herpetiformis, Duhring's disease: symptoms

Health Vitalitycross August 7, 2016 0 0
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Dermatitis herpetiformis, also known as "Duhring's disease, is a rare skin condition that is characterized by an itchy skin rash blistering and burning. Dermatitis herpetiformis is a very nasty skin condition where you can have a lot experience in daily life. The rash and itching mainly occur on the elbows, knees, scalp, back and buttocks. Dermatitis herpetiformis is a skin disease that is strongly associated with celiac disease, an intolerance to gluten.

Dermatitis herpetiformis

  • What is dermatitis herpetiformis?
  • What is the cause of dermatitis herpetiformis?
  • What are the symptoms of dermatitis herpetiformis?
  • How is it diagnosed?
  • How is dermatitis herpetiformis treated?

What is dermatitis herpetiformis?

The literal meaning of dermatitis herpetiformis is: skin inflammation similar to herpes. Dermatitis herpetiformis is also known under the name of disease of Duhring, to the doctor who first described for this disease. Dermatitis herpetiformis is characterized by very itchy blisters on typical skin areas and occurs in people with a sensitivity to gluten, which the intestinal celiac disease leads to. Yet it is not true that all patients with dermatitis herpetiformis intestinal complaints and patients with celiac disease have rarely dermatitis herpetiformis. Dermatitis herpetiformis is a rare condition.

What is the cause of dermatitis herpetiformis?

The name 'dermatitis herpetiformis' many people think that these results are caused by some form of the herpes virus. However, this is not true. Dermatitis herpetiformis occurs in people with celiac disease, an intolerance to gluten. Gluten is a protein found in wheat, rye, barley and oats. Gluten from the diet activate the defense of the body, wherein there are antibodies to be made against gliadin. These antibodies affect the intestinal mucosa and to the same type of antibodies can cause blisters in the skin. About 15 to 25 percent of people with celiac disease have DH. Celiac disease can also cause severe abdominal pain, constipation, nausea and vomiting. However, some people with DH have celiac disease, but none of the intestinal symptoms. Many people with dermatitis herpetiformis experience worsening of skin symptoms when they eat gluten-containing foods.
Dermatitis herpetiformis is also associated with other autoimmune disorders, such as:
  • diabetes;
  • rheumatism;
  • thyroid disease;
  • vitiligo; and
  • alopecia areata.

What are the symptoms of dermatitis herpetiformis?

In dermatitis herpetiformis, there are strong itchy red bumps and blisters to 1 cm in size, located in groups as is also the case with a herpes infection. There is the name herpetiformis, therefore, is based on, even though DH has nothing to do with "ordinary" herpes. The lesions are often symmetrically distributed and occur mainly on the elbows and knees, buttocks and scalp. They are not seen in the oral mucosa. The blisters may break easily scratched, with red bumps and scratch effects and -wondjes visible. Dermatitis herpetiformis, periods of exacerbations, interspersed with periods of recovery.

How is it diagnosed?

On suspicion of dermatitis herpetiformis, the diagnosis can be confirmed by the dermatologist by taking a skin biopsy for weefselonderzoek.Onder more, they look or IgA antibodies and neutrophils can be demonstrated. If you are suffering from intestinal disorders and celiac disease has not been established with you, you'll be referred to a gastroenterologist for internal intestine liver medical research, which will be taken darmbiopt for tissue research. Also, blood tests may be needed, which can be examined for the presence of specific antibodies against gluten and antibodies against intestinal tissue.

How is dermatitis herpetiformis treated?

Dermatitis herpetiformis is the cutaneous manifestation of coeliakie.¹ Cutaneous means "relating to the skin." Research shows that all patients with DH benefit from a gluten-free diet. The complaints there may fully disappear. Since it no easy task to maintain a gluten-free diet, it may be wise to switch to a dietician. In addition, often drug therapy will be necessary. The drug dapsone is most effective at DH. Within a few days you will see results already. Dapsone caused sometimes very unpleasant side effects such as anemia. There are alternatives, such as strong corticosteroïdzalven, but these are often less effective. Dermatitis herpetiformis is indeed a chronic condition, but with a gluten-free diet and adequate supervision of the dermatologist, internist and nutritionist complaints tend to get good control.
Note:
  • Tim G. J. de Meij and C. M. Frank Kneepkens. A girl with an itchy skin condition. Ned Tijdschr Geneeskd. 2012; 156: A4646
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