Obesity, arrive and fall; new insights

Health liv2die August 8, 2016 0 1
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Obesity seems to be the punishment of modern society for our lifestyle. Often the result of unhealthy and overeating coupled with little or no exercise at all. Those who battle with the kilos are there varying success. While some success losing weight and keeping with minimum hassle off, others are doomed to annoying yo-yo effect. Do they lack perseverance? Or other factors also play a role? New research provides insight.

Jojo effect; Genetically determined!

Internet is full of requests for help from people who follow a strict diet, lose weight, then go eat normally and arrive again. How can it do that a lot of people lose weight and then keep struggling for years with minimal weight, and others are doomed to eternal yo-yo effect? Which often also so that you still end up after every crash diet more arrive, and your weight so eventually rises? Do these people not enough perseverance or is there more to it?
Scientists from Maastricht University have discovered that it is genetically determined in part or yo-yo or a woman is going to hold its weight. A gene which is involved in the regulation of blood pressure also appears to play a role in the all that are susceptible to the yo-yo effect. It has to do with the level of the angiotensin-converting enzyme in the blood of the vrouwen.De scientists hope to be able to develop a test that can be already checked before the start of a diet or the woman will go yo-yo or not. On that basis, can be viewed or women need guidance from a dietitian to still be able to lose weight successfully.

FTO gene; responsible for obesity.

It is not surprising that a gene that stimulates appetite responsible for obesity. New research shows that there are two variants of this gene. If you inherit both variants have 70 percent more likely to be obese! And 50 percent more likely to have diabetes. In Europe, about 16 percent of people both variants. It is now busy working on a drug that can inhibit the action of this gene.

Obesity and diabetes 2

2 diabetes and obesity have been linked to the loss of the function of the gene CMAH in the course of human evolution. In modern humans, the evolution took a wrong turn, according to scientists at the Federation of American Societies for Experimental Biology. In many people, this gene loses its effect and therefore makes this group more susceptible to obesitias and diabetes 2. Loss of the operation of the CMAH gene also causes the pancreas to produce less insulin. This loss of function of the gene CMAH occurs only in humans, not in other mammals.
The investigation into the poorly functioning gene CMAH was done on two groups of mice. Group 1 had a normal CMAH gene. Group 2 had the same mutated variant of CMAH that occurs in humans. Both groups were eating fat, which makes them were with insulin resistance with obesity. In the group with the malfunctioning gene CMAH took off insulin production and blood sugar went fluctuate enormously.
With this breakthrough, researchers hope to better understand and develop a new treatment for type 2 diabetes in people with this gene failed. Perhaps further investigation also gives insight to the obesity that is related thereto.
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